TY - JOUR AU - Jaicharoensub, Jaiboonya AU - Sakpakdeecharoen, Intouch AU - Panthong,, Sumalee AU - Itharat, Arunporn PY - 2022/08/01 Y2 - 2024/03/28 TI - Biological Activities of Ya-Mor-Noi Remedy for Postpartum Care JF - Asian Medical Journal and Alternative Medicine JA - AMJAM VL - 22 IS - - SE - Abstracts DO - 10.14456/2022s10715 UR - https://asianmedjam.com/index.php/amjam/article/view/1323 SP - S106 AB - <p><strong>Introduction:</strong> Ya-Mor-Noi (YMN) is a Thai herbal remedy used at Dansai Crown Prince Hospital, Loei Province. It consists of seven plants, including the rhizome of <em>Smilax corbularia</em> (SC), the stem of <em>Caesalpinia sappan</em> (CS), <em>Goniothalamus laoticus</em> (GL), <em>Polyalthia suberosa</em> (PS), <em>Glycosmis pentaphylla</em> (GP), <em>Croton persimili</em>s (CP), and <em>Diospyros ehretioides</em> (DE). For over 20 years, YMN has been prescribed for patients admitted to post-partum wards after delivery to efficiently reduce inflammation and rehabilitate them.</p><p><strong>Objectives:</strong> To study biological activities of YMN extracts relating to postpartum conditions, including anti-inflammatory, wound healing activities and investigating its main compound.</p><p><strong>Methods:</strong> Extraction methods comprised maceration at 95%, ethanol at 50%, and decoction. Anti-inflammatory activity was investigated by determining the production of nitric oxide (NO) from RAW264.7 cells. Wound healing activity was investigated by scratch assay and the main compounds investigating through high-performance liquid chromatography (HPLC).</p><p><strong>Results:</strong> Ethanolic extracts of YMN showed inhibition of nitric production. The decoction extract showed significant difference in wound recovery compared to the control. HPLC fingerprint analysis indicated two main compounds: Brazilin and Astilbin.</p><p><strong>Conclusions:</strong> It is concluded that YMN produced anti-inflammatory and increased percentage of wound recovery. These findings support usage of YMN to treat postpartum patients by traditional medicine practitioners in Thailand.</p> ER -