New Antiretroviral Drugs in the Pandemic

Authors

  • Thana Khawcharoenporn Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand

DOI:

https://doi.org/10.14456/2022s10303

Keywords:

New, Antiretroviral drugs, Pandemic, HIV, Long-acting

Abstract

The pandemic of coronavirus disease-19 (COVID-19) has impacted the care of people living with human immunodeficiency virus (HIV) and HIV prevention in several ways. Locking down and limiting transportation to slow down COVID-19 transmission can cause difficulty accessing and non-compliance to daily-dosing antiretroviral drugs (ARVs). The new formu-lations of ARVs, including long-acting ones administered as injections and implants are being approved and developed for HIV treatment and prevention. Intramuscular cabotegravir and rilpivirine co-formulation is approved by the US Food and Drug Administration for HIV treatment in virologically suppressed adults on a stable regimen, while intramuscular cabotegravir is approved for HIV pre-exposure prophylaxis. Other long-acting drugs, such as lenacapavir and islatravir have currently been developed and studied for HIV treatment and/or prevention. This present article concisely reviews the current knowledge on these new ARVs and their implications, which may serve as novel regimens for use during the current and future pandemics.

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Published

2022-08-01

How to Cite

[1]
Khawcharoenporn, T. 2022. New Antiretroviral Drugs in the Pandemic. Asian Medical Journal and Alternative Medicine. 22, - (Aug. 2022), S50-S61. DOI:https://doi.org/10.14456/2022s10303.