In Vitro α-Amylase, α-Glucosidase Inhibition, and Anti-Oxidant Activities of Plant Components in Ya-Hom Teppajid


  • Pannawat Chaiyawathanananthn Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
  • Wantana Duangsri Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
  • Arunporn Itharat Center of Excellence in Applied Thai Traditional Medicine Research (CEATMR), Thammasat University, Pathum Thani, Thailand.
  • Weerachai Pipatrattanaseree Regional Medical Science Center 12 Songkhla, Department of Medical Science, Ministry of Public Health, Muang, Songkhla, Thailand
  • Buncha Ooraikul Department of Agricultural food and Nutritional Science, Faculty of Agricultural Life and Environmental Sciences, University of Alberta, Edmonton, Canada



Ya-Hom Teppajid, α-amylase, α-glucosidase, Diabetes mellitus, Antioxidant


Introduction: Diabetes is characterized by high blood sugar levels or hyperglycemia causing the increase of free radicals which increase the risk of various diseases. Ya-Hom Teppajid which consists of 45 plants and their properties had shown anti-diabetic activities in some herbs and the rest of the herbs have not been studied for these activities.
Methods: The ethanolic extract of plant componentsinYa-Hom Teppajid were to investigate α-amylase, α-glucosidase inhibitory, and antioxidant activities (DPPH, and TBARS), including total phenolic (TPC) and total flavonoid (TFC).
Results: Twenty-four plants showed antioxidant activities, while fifteen plants exhibited enzyme inhibition of diabetes mechanisms. The ethanolic extract of N. lotus had stronger enzyme inhibitory activities and antioxidant activities than other plant components, although less than the positive standard.
Conclusions: Our result can support the efficacy of Ya-Hom-Teppajid for a diabetic. Interestingly, the whole flower of N. lotus was suggested as a better part due to its stronger antioxidant activity by free radicals scavenging property. These herbs can be consumed as food ingredients or food supplements and their consumption should be beneficial to diabetic patients.


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The Pearson statistical correlation scatters plot of the linear relationship between (A) DPPH and TPC, (B) DPPH and TFC, (C) TBARS and TPC, and (D) TBARS and TFC.




How to Cite

Chaiyawathanananthn, P., Duangsri, W. , Itharat, A. , Pipatrattanaseree, W. and Ooraikul, B. 2022. In Vitro α-Amylase, α-Glucosidase Inhibition, and Anti-Oxidant Activities of Plant Components in Ya-Hom Teppajid. Asian Medical Journal and Alternative Medicine. 22, - (Aug. 2022), S22-S32. DOI:



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