The Utility of Preoperative CT Scans for the Differentiation of Mucinous versus Non-mucinous Colorectal Adenocarcinoma

Authors

  • Piyaporn Apisarnthanarak Department of Radiology, Faculty of Medicine, Thammasat University
  • Sirudcha Polsak Department of Radiology, Faculty of Medicine, Thammasat University
  • Voraparee Suvannarerg Department of Radiology, Faculty of Medicine, Thammasat University
  • Vilasinee Rerkpichaisuth Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Kobkun Muangsomboon Department of Radiology, Faculty of Medicine, Thammasat University
  • Wanwarang Teerasamit Department of Radiology, Faculty of Medicine, Thammasat University
  • Sopa Pongpornsup Department of Radiology, Faculty of Medicine, Thammasat University
  • Anucha Apisarnthanarak Division of Infectious Diseases, Thammasat University Hospital

Keywords:

Colorectal CA, Computed tomography (CT), Mucinous adenocarcinoma, Non-mucinous adenocarcinoma, Preoperative evaluation

Abstract

Objectives:     To assess the characteristics of mucinous versus non-mucinous colorectaladenocarcinoma by preoperative computed tomography (CT) scans.

Methods:        A retrospective study was conducted over a 12-year, 6-month period for a comparative assessment of preoperative abdominal CT scans in 143 participants postoperatively confirmed with either mucinous (47 participants) or non-mucinous colorectal adenocarcinoma (96 participants). Two experienced abdominal radiologists separately conducted a blinded review of preoperative CT scans for tumor characterization. A stratified comparative analysis was performed.

Results:          The mean tumor diameter and length were significantly greater in the mucinous group (p-value < 0.001). The presence of heterogeneous enhancement and an area of hypoattenuation greater than two-thirds of the tumor volume were more frequently visualized in the mucinous group (p-value = 0.001 and p-value < 0.001, respectively). Tumor characterization as a heterogeneous enhancement plus an area of hypoattenuation more than two-thirds of the tumor volume had diagnostic utility for mucinous adenocarcinoma with a sensitivity, specificity, and accuracy of 66.0%, 95.8%, and 86.0%, respectively.

Conclusions:  Preoperative CT scans have potential for differentiation of mucinous versus non-mucinous colorectal adenocarcinoma.

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References

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Published

2023-08-30

How to Cite

[1]
Apisarnthanarak, P., Polsak, S., Suvannarerg, V., Rerkpichaisuth, V., Muangsomboon, K., Teerasamit, W., Pongpornsup, S. and Apisarnthanarak, A. 2023. The Utility of Preoperative CT Scans for the Differentiation of Mucinous versus Non-mucinous Colorectal Adenocarcinoma. Asian Medical Journal and Alternative Medicine. 23, 2 (Aug. 2023), 129–138.

Issue

Vol. 23 No. 2 (2023): May-August

Section

Original Articles

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