Correlation of Size and Redness of Pterygium on Tear Film and Dry Eye Symptoms

Abstract

Purpose: This study aimed to evaluate affecting size and redness of pterygium to tear film and dry eye symptoms.

Setting/Venue: Thammasat University Hospital, Thailand

Method: 976 patients was joined in hospital-based, cross-sectional study was performed at Thammasat University Hospital, Thailand. Severity of pterygium was collected by size and redness; Tear film was collected by Tear meniscus (TMH) and Tear break up time (TBUT); Dry eye syndrome was collected by Ocular surface visual analogue scale (VAS), Ocular Surface Disease Index (OSDI), Oxford corneal staining scale and Meibomian gland dysfunction grading. The study was analyzed by correlation by using statistical tools of simple linear regression, Pearson correlation and Anova.

Results: 328 pterygium patients were collected. An average 2.74 mm, 2.45 clock hours were horizontal and vertical size of pterygium. The most common redness grading is intermediate (176/328:53.66%). Relationship between horizontal, vertical size and redness of pterygium (R = 0.32, 0.29 and 0.64) at significant <0.001, 0.005 and <0.001).The strongest correlation was found in redness of pterygium with OSDI scores, TBUT and Oxford corneal staining scale (R=0.58,-0.46 and 0.38) at significant <0.001.

Conclusion: Pterygium patients were found to 33.6 percent in hospital-base. Horizontal, Vertical size and redness of pterygium were related to tear film and dry eye symptoms. Redness of pterygium was the most importance clinical feature affected to tear film and dry eye symptoms.