An Initial Report on Operability and Safety of A Domestic Automated Peritoneal Dialysis Machine in Thailand

Authors

  • Opas Traitanon Department of Medicine-Nephrology, Thammasat University Hospital, Pathum Thani, Thailand
  • Thanarak Boongerd 60th Anniversary HRH Princess Maha Chakri Sirindhorn Dialysis Center, Thammasat University Hospital, Pathum Thani, Thailand
  • Songphon Dumnin Assistive Technology and Medical Devices Research Center, National Science and Technology Development Agency, Pathum Thani, Thailand
  • Chatchai Buekban Assistive Technology and Medical Devices Research Center, National Science and Technology Development Agency, Pathum Thani, Thailand
  • Ronachai Pongthornseri Assistive Technology and Medical Devices Research Center, National Science and Technology Development Agency, Pathum Thani, Thailand
  • Supat Sampnyuth Assistive Technology and Medical Devices Research Center, National Science and Technology Development Agency, Pathum Thani, Thailand
  • Chusak Thanawattano Assistive Technology and Medical Devices Research Center, National Science and Technology Development Agency, Pathum Thani, Thailand
  • Decho Surangsrirat Assistive Technology and Medical Devices Research Center, National Science and Technology Development Agency, Pathum Thani, Thailand

Keywords:

Automated peritoneal dialysis machine, Peritoneal dialysis, End-stage renal disease, Universal health coverage scheme

Abstract

Background: Thailand had implemented the peritoneal dialysis first (PD first) policy which allowed access to peritoneal dialysis as a first-line treatment for end-stage renal disease (ESRD). However, all the patients under this policy are allowed to use only the self-operated Continuous Ambulatory Peritoneal Dialysis (CAPD) but not the Automated Peritoneal Dialysis (APD). While APD has a lot of advantages over CAPD, its cost is more than double in Thailand. Under these circumstances, it is crucial to produce APD equipment with a trade-off between good performance and affordable price.

Methods: This study is a pilot cross-sectional study to evaluate the operability and safety of the domestically developed APD machine. Three stable ESRD patients already treated with APD machines were recruited for the 7-day trial.

Results: There is a slight decrease in the dwell time due to the longer operational time of the developed machine; 11.26 ± 2.29%. Increases in serum creatinine and blood urea nitrogen were observed; 3.01 ± 1.83% and 22.92 ± 4.48%, respectively. No major adverse events were reported.

Conclusion: The developed machine used only gravity for the exchange, the dwell time was decreased as expected, resulting in a lower exchange of the waste products from the blood to the peritoneal cavity. Even though the results show a slightly lower treatment performance, no clinical significance during short-term follow-up was observed. To obtain similar performance for the domestically developed APD machine, total treatment time could be increased to maintain comparable dwell time overnight.

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References

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Published

2021-08-27

How to Cite

[1]
Traitanon, O., Boongerd, T., Dumnin, S., Buekban, C., Pongthornseri, R., Sampnyuth, S., Thanawattano, C. and Surangsrirat, D. 2021. An Initial Report on Operability and Safety of A Domestic Automated Peritoneal Dialysis Machine in Thailand. Asian Medical Journal and Alternative Medicine. 21, 2 (Aug. 2021), 91–96.

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Original Articles